circSIRT2/miR-542-3p/VASH1 axis regulates endothelial-to-mesenchymal transition (EndMT) in subretinal fibrosis in age-related macular degeneration models.

Authors: Zhang M; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.; National Clinical Research Center for Ophthalmic Diseases, Shanghai, China., Wu J; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.; National Clinical Research Center for Ophthalmic Diseases, Shanghai, China., Wang Y; Department of Ophthalmology, Zhongshan Hospital, Fudan University, Shanghai, China., Wu Y; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.; National Clinical Research Center for Ophthalmic Diseases, Shanghai, China., Wan X; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.; National Clinical Research Center for Ophthalmic Diseases, Shanghai, China., Jiang M; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.; National Clinical Research Center for Ophthalmic Diseases, Shanghai, China., Bo Q; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.; National Clinical Research Center for Ophthalmic Diseases, Shanghai, China., Chen J; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.; National Clinical Research Center for Ophthalmic Diseases, Shanghai, China., Sun X; Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.; National Clinical Research Center for Ophthalmic Diseases, Shanghai, China.; Shanghai Key Laboratory of Fundus Diseases, Shanghai, China.; Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China.

Source: Aging cell [Aging Cell] 2025 Apr; Vol. 24 (4), pp. e14443. Date of Electronic Publication: 2025 Jan 02.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE

MeSH Terms: MicroRNAs*/metabolism , MicroRNAs*/genetics , RNA, Circular*/genetics , RNA, Circular*/metabolism , Macular Degeneration*/genetics , Macular Degeneration*/pathology , Macular Degeneration*/metabolism , Epithelial-Mesenchymal Transition*/genetics , Cell Cycle Proteins*/metabolism , Cell Cycle Proteins*/genetics , Retina*/pathology , Retina*/metabolism, Humans ; Animals ; Mice ; Fibrosis ; Disease Models, Animal ; Human Umbilical Vein Endothelial Cells ; Choroidal Neovascularization ; Endothelial-Mesenchymal Transition

Continuation of Pediatric Care after Transfer to Adult Care Among Autistic Youth Overlap of Pediatric and Adult Care.

Authors: Sirrianni J; Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA., Hanks C; The Ohio State University College of Medicine, Columbus, OH, USA., Rust S; Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA., Hart LC; Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA. laura.hart@nationwidechildrens.org.; The Ohio State University College of Medicine, Columbus, OH, USA. laura.hart@nationwidechildrens.org.

Source: Journal of autism and developmental disorders [J Autism Dev Disord] 2025 Apr; Vol. 55 (4), pp. 1203-1214. Date of Electronic Publication: 2024 Mar 23.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 7904301 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-3432 (Electronic) Linking ISSN: 01623257 NLM ISO Abbreviation: J Autism Dev Disord Subsets: MEDLINE

MeSH Terms: Transition to Adult Care*/statistics & numerical data , Primary Health Care*/statistics & numerical data , Autistic Disorder*/therapy, Humans ; Male ; Female ; Adolescent ; Young Adult ; Adult ; Electronic Health Records ; Cohort Studies

Insights into healthcare services for youth with autism spectrum disorder transitioning to adulthood: a focus on rural Atlantic Canada.

Authors: Ghanouni P; Department of Occupational Therapy, Dalhousie University, PO Box 15000, Halifax, NS, B3H 4R2, Canada. parisa.ghanouni@alumni.ubc.ca., Naimpally T; Department of Occupational Therapy, Dalhousie University, PO Box 15000, Halifax, NS, B3H 4R2, Canada.

Source: BMC health services research [BMC Health Serv Res] 2025 Apr 23; Vol. 25 (1), pp. 584. Date of Electronic Publication: 2025 Apr 23.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088677 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6963 (Electronic) Linking ISSN: 14726963 NLM ISO Abbreviation: BMC Health Serv Res Subsets: MEDLINE

MeSH Terms: Autism Spectrum Disorder*/therapy , Transition to Adult Care*/organization & administration , Health Services Accessibility* , Rural Health Services*, Humans ; Adolescent ; Male ; Qualitative Research ; Female ; Canada ; Adult ; Young Adult ; Rural Population ; Interviews as Topic ; Continuity of Patient Care ; Parents/psychology

Modulation of the Epithelial-mesenchymal transition process by Forkhead Box C2 in the repair of airway epithelium after injury.

Authors: Wang Y; Department of Thoracic Surgery, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, People's Republic of China., Liu J; Department of Thoracic Surgery, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Shenyang, People's Republic of China. jliu74@cmu.edu.cn.

Source: Respiratory research [Respir Res] 2025 Mar 10; Vol. 26 (1), pp. 96. Date of Electronic Publication: 2025 Mar 10.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/physiology , Forkhead Transcription Factors*/genetics , Forkhead Transcription Factors*/biosynthesis , Forkhead Transcription Factors*/metabolism , Respiratory Mucosa*/metabolism , Respiratory Mucosa*/pathology , Respiratory Mucosa*/injuries , Wound Healing*/physiology, Animals ; Mice, Inbred C57BL ; Mice ; Male ; Cells, Cultured

Circ_RPPH1 promotes bladder urothelium carcinoma proliferation and EMT by recruiting and binding to EIF4 A3.

Authors: Liu H; Department of Urology, Deyang People's Hospital, Sichuan Province, Deyang City, 618000, China., Ma J; Department of Urology, Huaian Hospital of Huaian City, Huaian City, Jiangsu Province, 223200, China., Yan X; Department of Inspection Division, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei Province, No.1 Zhongyuan Road, Xiangyang City, 441003, China. YANXIA-yanxia1359@hotmail.com.

Source: Hereditas [Hereditas] 2025 May 09; Vol. 162 (1), pp. 72. Date of Electronic Publication: 2025 May 09.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 0374654 Publication Model: Electronic Cited Medium: Internet ISSN: 1601-5223 (Electronic) Linking ISSN: 00180661 NLM ISO Abbreviation: Hereditas Subsets: MEDLINE

MeSH Terms: Urinary Bladder Neoplasms*/genetics , Urinary Bladder Neoplasms*/pathology , Eukaryotic Initiation Factor-4A*/metabolism , Eukaryotic Initiation Factor-4A*/genetics , Epithelial-Mesenchymal Transition*/genetics , RNA, Circular*/genetics, Humans ; Cell Proliferation/genetics ; Cell Line, Tumor ; Cadherins/genetics ; Gene Expression Regulation, Neoplastic ; Urothelium/pathology ; Cell Movement ; Male ; Female ; Vimentin/genetics ; Vimentin/metabolism ; DEAD-box RNA Helicases

DERL3 facilitates the progression of clear cell renal cell carcinoma by promoting epithelial-mesenchymal transition via regulation of the TGFB1 pathway.

Authors: Niu C; Department of Urology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China.; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Cui H; Department of Urology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China.; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Sun X; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Yang Y; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Jiang X; Shandong Xiehe University, Jinan, China., Cong Z; Department of Urology, Weihai Municipal Hospital Affiliated to Shandong University, Weihai, China., Zhang Y; Department of Urology, People's Hospital of Changle County, Weifang, Shandong, China., Niu Z; Department of Urology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China.; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., He W; Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.

Source: PloS one [PLoS One] 2025 Apr 29; Vol. 20 (4), pp. e0322172. Date of Electronic Publication: 2025 Apr 29 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/genetics , Carcinoma, Renal Cell*/pathology , Carcinoma, Renal Cell*/metabolism , Carcinoma, Renal Cell*/genetics , Kidney Neoplasms*/pathology , Kidney Neoplasms*/metabolism , Kidney Neoplasms*/genetics , Transforming Growth Factor beta1*/metabolism , Transforming Growth Factor beta1*/genetics , Membrane Proteins*/genetics , Membrane Proteins*/metabolism, Humans ; Cell Line, Tumor ; Disease Progression ; Gene Expression Regulation, Neoplastic ; Prognosis ; Signal Transduction ; Female ; Male ; Cell Movement

Epigenomic disorder and partial EMT impair luminal progenitor integrity in Brca1-associated breast tumorigenesis.

Authors: Landragin C; Institut Curie, CNRS UMR3244, PSL University, Paris, France.; Translational Research Department, Institut Curie, PSL University, Paris, France.; Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland., Saichi M; Institut Curie, CNRS UMR3244, PSL University, Paris, France.; Translational Research Department, Institut Curie, PSL University, Paris, France., Laisné M; Institut Curie, CNRS UMR3244, PSL University, Paris, France.; Translational Research Department, Institut Curie, PSL University, Paris, France., Durand A; Institut Curie, CNRS UMR3244, PSL University, Paris, France.; Translational Research Department, Institut Curie, PSL University, Paris, France., Prompsy P; Institut Curie, CNRS UMR3244, PSL University, Paris, France.; Translational Research Department, Institut Curie, PSL University, Paris, France.; Department of Dermatology, Faculty of Biology and Medicine, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland., Leclere R; Department of Pathology-Genetics and Immunology, Institut Curie, PSL University, Paris, France., Mesple J; Institut Curie, INSERM U932, Equipe Leader Fondation ARC, PSL University, Paris, France., Borgman K; Single Cell Initiative, Institut Curie, PSL University, Paris, France.; Institut Curie, CNRS UMR3664, PSL University, Paris, France., Trouchet A; Institut Curie, CNRS UMR3244, PSL University, Paris, France.; Single Cell Initiative, Institut Curie, PSL University, Paris, France., Faraldo MM; Inserm U934, Institut Curie, CNRS UMR3215, PSL University, Paris, France., Chiche A; Cellular Plasticity and Disease Modelling, Department of Developmental and Stem Cell Biology, UMR 3738, CNRS, Institut Pasteur, Paris, France., Vincent-Salomon A; Department of Pathology-Genetics and Immunology, Institut Curie, PSL University, Paris, France.; INSERM U934, Institut Curie, PSL University, Paris, France., Salmon H; Institut Curie, INSERM U932, Equipe Leader Fondation ARC, PSL University, Paris, France., Vallot C; Institut Curie, CNRS UMR3244, PSL University, Paris, France. celine.vallot@curie.fr.; Translational Research Department, Institut Curie, PSL University, Paris, France. celine.vallot@curie.fr.; Single Cell Initiative, Institut Curie, PSL University, Paris, France. celine.vallot@curie.fr.

Source: Molecular cancer [Mol Cancer] 2025 Apr 28; Vol. 24 (1), pp. 127. Date of Electronic Publication: 2025 Apr 28.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE

MeSH Terms: BRCA1 Protein*/genetics , BRCA1 Protein*/metabolism , Epithelial-Mesenchymal Transition*/genetics , Breast Neoplasms*/genetics , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Epigenomics*/methods , Cell Transformation, Neoplastic*/genetics , Neoplastic Stem Cells*/metabolism , Neoplastic Stem Cells*/pathology, Humans ; Female ; Animals ; Mice ; Carcinogenesis/genetics ; Mutation ; Gene Expression Regulation, Neoplastic ; Tumor Microenvironment

Extracellular vesicles from adipose-derived mesenchymal stem cells promote colony formation ability and EMT of corneal limbal epithelial cells.

Authors: Li X; Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan., Hayashi R; Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Osaka, Japan., Imaizumi T; Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Basic Research Development Division, ROHTO Pharmaceutical, Ikuno-ku, Osaka, Japan., Harrington J; Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Faculty of Health, Medicine and Social Care, Medical Technology Research Centre, Anglia Ruskin University, Chelmsford Campus, England, United Kingdom., Kudo Y; Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Basic Research Development Division, ROHTO Pharmaceutical, Ikuno-ku, Osaka, Japan., Takayanagi H; Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Research, Development and Production Department of RAYMEI Inc, Suita, Osaka, Japan., Baba K; Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Department of Advanced Device Regenerative Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Visual Regenerative Medicine, Division of Health Sciences, Osaka University Graduate School of Medicine, Suita, Osaka, Japan., Nishida K; Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Osaka, Japan.

Source: PloS one [PLoS One] 2025 Apr 21; Vol. 20 (4), pp. e0321579. Date of Electronic Publication: 2025 Apr 21 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Extracellular Vesicles*/metabolism , Epithelial-Mesenchymal Transition* , Limbus Corneae*/cytology , Limbus Corneae*/metabolism , Epithelial Cells*/metabolism , Epithelial Cells*/cytology , Epithelium, Corneal*/cytology , Epithelium, Corneal*/metabolism , Adipose Tissue*/cytology, Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Cell Proliferation ; Cell Movement ; Cells, Cultured

Scutellaria Barbata inhibits epithelial-mesenchymal transformation through PI3K/AKT and MDM2 thus inhibiting the proliferation, migration and promoting apoptosis of Cervical Cancer cells.

Authors: Wang G; Medical Research Laboratory, YiBin Hospital of T.C.M, Yibin, China., Jia C; Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China., Wang D; Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Sichuan Province Engineering Technology Research Center of Molecular Diagnosis of Clinical Diseases, Luzhou, China.; Molecular Diagnosis of Clinical Diseases Key Laboratory of Luzhou, Luzhou, China., Liang L; Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Sichuan Province Engineering Technology Research Center of Molecular Diagnosis of Clinical Diseases, Luzhou, China.; Molecular Diagnosis of Clinical Diseases Key Laboratory of Luzhou, Luzhou, China., Li L; Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Sichuan Province Engineering Technology Research Center of Molecular Diagnosis of Clinical Diseases, Luzhou, China.; Molecular Diagnosis of Clinical Diseases Key Laboratory of Luzhou, Luzhou, China., Tian G; Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, Luzhou, China.; Sichuan Province Engineering Technology Research Center of Molecular Diagnosis of Clinical Diseases, Luzhou, China.; Molecular Diagnosis of Clinical Diseases Key Laboratory of Luzhou, Luzhou, China., Feng W; Medical Research Laboratory, YiBin Hospital of T.C.M, Yibin, China.

Source: PloS one [PLoS One] 2025 Apr 16; Vol. 20 (4), pp. e0321556. Date of Electronic Publication: 2025 Apr 16 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Uterine Cervical Neoplasms*/pathology , Uterine Cervical Neoplasms*/metabolism , Uterine Cervical Neoplasms*/drug therapy , Uterine Cervical Neoplasms*/genetics , Apoptosis*/drug effects , Proto-Oncogene Proteins c-mdm2*/metabolism , Scutellaria*/chemistry , Epithelial-Mesenchymal Transition*/drug effects , Plant Extracts*/pharmacology, Humans ; Female ; Cell Proliferation/drug effects ; Cell Movement/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; HeLa Cells ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction/drug effects ; Flavonoids/pharmacology ; Gene Expression Regulation, Neoplastic/drug effects ; Flavanones/pharmacology ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism

Establishment of a simple prediction method for DNA melting temperature: high-resolution melting curve analysis of PCR products.

Authors: Zhou Y; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Ha S; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Xu Y; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Qin X; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Ma Y; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Lu J; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Wang B; Hainan Vocational College of Political Science and Law, Haikou, China., Cai J; Hainan Vocational College of Political Science and Law, Haikou, China., Duan Z; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Cong B; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.; Department of Forensic Medicine, Hebei Medical University, Shijiazhuang, China., Chen J; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China., Deng J; Hainan Provincial Tropical Forensic Engineering Research Center & Hainan Provincial Academician Workstation (Tropical Forensic Medicine), Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Basic Medicine and Life Sciences, Hainan Medical University, Haikou, China.

Source: PloS one [PLoS One] 2025 Apr 16; Vol. 20 (4), pp. e0321885. Date of Electronic Publication: 2025 Apr 16 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: DNA*/chemistry , DNA*/genetics , Nucleic Acid Denaturation* , Transition Temperature* , Polymerase Chain Reaction*/methods, Base Composition ; Thermodynamics

Deciphering the anti-neoplastic potential of Allium ascalonicum in averting the proliferation and epithelial-mesenchymal transition of triple-negative breast cancer through virtual docking and In Vitro approaches.

Authors: Ravindranath KJ; School of Life Sciences, B. S. Abdur Rahman Crescent Institute of Science & Technology, Vandalur, Chennai, 600048, India., Srinivasan H; School of Life Sciences, B. S. Abdur Rahman Crescent Institute of Science & Technology, Vandalur, Chennai, 600048, India. hemalatha.sls@bsauniv.ac.in.

Source: BMC cancer [BMC Cancer] 2025 Mar 07; Vol. 25 (1), pp. 414. Date of Electronic Publication: 2025 Mar 07.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/drug effects , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/metabolism , Plant Extracts*/pharmacology , Plant Extracts*/chemistry , Allium*/chemistry , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/chemistry, Humans ; Cell Proliferation/drug effects ; Molecular Docking Simulation ; Cell Line, Tumor ; Female ; Cell Movement/drug effects ; Apoptosis/drug effects

A Socioecological Approach to Support the Transition to Adult Care for Youth With Medical Complexity: Family Perspectives and Recommendations.

Authors: Li L; School of Nursing, McMaster University, Hamilton, Ontario, Canada., Carter N; School of Nursing, McMaster University, Hamilton, Ontario, Canada., Gorter JW; University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.; CanChild Centre for Childhood Disability Research, McMaster University, Hamilton, Ontario, Canada., Till L; School of Nursing, McMaster University, Hamilton, Ontario, Canada., White M; School of Nursing, McMaster University, Hamilton, Ontario, Canada., Strachan PH; School of Nursing, McMaster University, Hamilton, Ontario, Canada.

Source: Health expectations : an international journal of public participation in health care and health policy [Health Expect] 2025 Feb; Vol. 28 (1), pp. e70077.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 9815926 Publication Model: Print Cited Medium: Internet ISSN: 1369-7625 (Electronic) Linking ISSN: 13696513 NLM ISO Abbreviation: Health Expect Subsets: MEDLINE

MeSH Terms: Transition to Adult Care* , Qualitative Research* , Family*/psychology, Humans ; Female ; Male ; Ontario ; Adolescent ; Young Adult ; Adult ; Interviews as Topic ; Chronic Disease/therapy ; Social Support

Stepping into adulthood: pediatric cancer survivors and their parents' perspectives on the transition from pediatric to adult care.

Authors: Ekaterina A; Institute of Social Medicine and Health Systems Research, Faculty of Medicine, Otto von Guericke University, Magdeburg, Germany. ekaterina.aleshchenko@med.ovgu.de., Thorsten L; University Hospital of Schleswig-Holstein, Campus Lübeck, Lübeck, Germany., Gabriele C; Department of Pediatric Hematology and Oncology, University Hospital Bonn, Bonn, Germany., Juliane G; Department of Pediatric Hematology and Oncology, University Hospital Bonn, Bonn, Germany., Swart E; Institute of Social Medicine and Health Systems Research, Faculty of Medicine, Otto von Guericke University, Magdeburg, Germany., Baust K; Department of Pediatric Hematology and Oncology, University Hospital Bonn, Bonn, Germany.

Source: BMC health services research [BMC Health Serv Res] 2025 Feb 04; Vol. 25 (1), pp. 204. Date of Electronic Publication: 2025 Feb 04.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088677 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6963 (Electronic) Linking ISSN: 14726963 NLM ISO Abbreviation: BMC Health Serv Res Subsets: MEDLINE

MeSH Terms: Transition to Adult Care*/organization & administration , Parents*/psychology , Cancer Survivors*/psychology , Neoplasms*/therapy , Neoplasms*/psychology, Humans ; Male ; Female ; Adolescent ; Adult ; Germany ; Qualitative Research ; Interviews as Topic ; Young Adult ; Child ; Middle Aged

Bringing Young People, Health and Social Care Professionals, Transition Champions and Policymakers Together Through Hybrid Methods of Participation: Creating a Space for Shared Understanding of What Is Required to Improve Young People's Healthcare Transition.

Authors: Porter L; The Burdett National Transition Nursing Network, England.; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Gibson F; School of Health Sciences, University of Surrey, Guildford, UK.; The Centre for Outcomes and Experience Research in Children's Health, Illness and Disability, Great Ormond Street Hospital, London, UK.; UCL Faculty of Population Health Sciences, UCL Great Ormond Street Institute of Child Health, London, UK., Aldiss S; School of Health Sciences, University of Surrey, Guildford, UK., Morgan S; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Stanton A; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Carney S; The Burdett National Transition Nursing Network, England.; Somerset Healthcare Foundation Trust, Somerset, UK., Farooq A; CYP Transformation Programme Board at NHS England, UK.; NHS Assembly Member at NHS England, UK., Barlow I; The Burdett National Transition Nursing Network, England., Sultan H; CYP Transformation Programme Board at NHS England, UK.; NHS WEST Yorkshire Integrated Care Board, UK., Sipanoun P; School of Health Sciences, University of Surrey, Guildford, UK.; The Centre for Outcomes and Experience Research in Children's Health, Illness and Disability, Great Ormond Street Hospital, London, UK.; UCL Faculty of Population Health Sciences, UCL Great Ormond Street Institute of Child Health, London, UK.

Source: Health expectations : an international journal of public participation in health care and health policy [Health Expect] 2025 Feb; Vol. 28 (1), pp. e70136.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 9815926 Publication Model: Print Cited Medium: Internet ISSN: 1369-7625 (Electronic) Linking ISSN: 13696513 NLM ISO Abbreviation: Health Expect Subsets: MEDLINE

MeSH Terms: Transition to Adult Care*/organization & administration , Stakeholder Participation* , Health Personnel* , Social Workers* , Administrative Personnel*, Humans ; England ; Quality Improvement ; Adolescent ; Young Adult ; State Medicine ; Adult

Elevated miR-221-3p inhibits epithelial-mesenchymal transition and biochemical recurrence of prostate cancer via targeting KPNA2: an evidence-based and knowledge-guided strategy.

Authors: Li D; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Department of Urology, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China., Jian J; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Department of Urology, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China., Shi M; College of Information and Network Engineering, Anhui Science and Technology University, Bengbu, 233000, China., Chen Z; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China.; Department of Urology, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China., Zhao A; Department of Urology, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China., Wei X; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China., Huang Y; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China., Chen Y; Department of Medical Informatics, School of Medicine, Nantong University, Nantong, 226001, China. ylchen@ntu.edu.cn., Hou J; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. xf192@163.com.; Department of Urology, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China. xf192@163.com., Lin Y; Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, 215006, China. linyuxin@suda.edu.cn.; Center for Systems Biology, Soochow University, Suzhou, 215123, China. linyuxin@suda.edu.cn.

Source: BMC cancer [BMC Cancer] 2025 Jan 08; Vol. 25 (1), pp. 34. Date of Electronic Publication: 2025 Jan 08.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

MeSH Terms: MicroRNAs*/genetics , Epithelial-Mesenchymal Transition*/genetics , Prostatic Neoplasms*/genetics , Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/metabolism , alpha Karyopherins*/genetics , alpha Karyopherins*/metabolism , Neoplasm Recurrence, Local*/genetics , Neoplasm Recurrence, Local*/pathology , Gene Expression Regulation, Neoplastic*, Humans ; Male ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Movement/genetics ; Prognosis

Navigating the Transition to Adulthood: Insights from Caregivers of Autistic Individuals.

Authors: Wolpe SM; Department of Education, University of California, Moore Hall, 457 Portola Plaza, Los Angeles, CA, 90095, USA. samarawolpe@g.ucla.edu., Johnson AR; Department of Education, University of California, Moore Hall, 457 Portola Plaza, Los Angeles, CA, 90095, USA., Kim S; University of California, Santa Barbara, Professional and Continuing Education, Santa Barbara, CA, USA.

Source: Journal of autism and developmental disorders [J Autism Dev Disord] 2025 Jan; Vol. 55 (1), pp. 166-180. Date of Electronic Publication: 2023 Dec 23.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 7904301 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-3432 (Electronic) Linking ISSN: 01623257 NLM ISO Abbreviation: J Autism Dev Disord Subsets: MEDLINE

MeSH Terms: Caregivers*/psychology , Autistic Disorder*/psychology , Transition to Adult Care* , Parents*/psychology, Humans ; Male ; Female ; Young Adult ; Adult ; Adolescent ; Middle Aged ; Qualitative Research

Detecting epithelial-mesenchymal transition signaling molecules in cervical epithelial cells aids in the early diagnosis of cervical lesions.

Authors: Zhang Z; Clinical Laboratory, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, P. R. China. zhanfengyy@yeah.net., Xie C; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, P. R. China., Zhao R; Clinical Laboratory, Guangzhou 8th People's Hospital, Guangzhou Medical University, Guangzhou, Guangdong, 510060, P. R. China., Wang S; Gynecology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, P. R. China., Xie Z; Clinical Laboratory, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, P. R. China., Pang Z; Clinical Laboratory, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, P. R. China., Xu Q; Clinical Laboratory, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510405, P. R. China., Zhang P; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, P. R. China. nfyyzp@126.com., Liu Y; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, P. R. China. liuyr2303@yeah.net.

Source: BMC cancer [BMC Cancer] 2024 Dec 27; Vol. 24 (1), pp. 1582. Date of Electronic Publication: 2024 Dec 27.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/genetics , Uterine Cervical Neoplasms*/diagnosis , Uterine Cervical Neoplasms*/virology , Uterine Cervical Neoplasms*/pathology , Uterine Cervical Neoplasms*/metabolism , Epithelial Cells*/metabolism , Epithelial Cells*/pathology , Epithelial Cells*/virology , Early Detection of Cancer*/methods, Humans ; Female ; Adult ; Middle Aged ; Papillomavirus Infections/diagnosis ; Papillomavirus Infections/virology ; Uterine Cervical Dysplasia/diagnosis ; Uterine Cervical Dysplasia/virology ; Uterine Cervical Dysplasia/pathology ; Uterine Cervical Dysplasia/metabolism ; Cervix Uteri/pathology ; Cervix Uteri/metabolism ; Cervix Uteri/virology ; Biomarkers, Tumor/metabolism ; Signal Transduction

MiR-454-3p regulates high glucose-induced mesothelial-mesenchymal transition and glycolysis in peritoneal mesothelial cells by targeting STAT3.

Authors: Li N; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Fu J; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Wang Q; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Rao Q; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Yao L; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Shao X; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Zhang P; Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

Source: Renal failure [Ren Fail] 2024 Dec; Vol. 46 (2), pp. 2394635. Date of Electronic Publication: 2024 Aug 27.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

MeSH Terms: MicroRNAs*/metabolism , MicroRNAs*/genetics , STAT3 Transcription Factor*/metabolism , Epithelial-Mesenchymal Transition*/drug effects , Glucose*/metabolism , Glucose*/pharmacology , Glycolysis*/drug effects , Peritoneal Dialysis*/adverse effects , Peritoneal Fibrosis*/metabolism , Peritoneal Fibrosis*/pathology , Peritoneal Fibrosis*/etiology , Peritoneal Fibrosis*/genetics , Peritoneum*/pathology , Peritoneum*/metabolism, Humans ; Male ; Female ; Middle Aged ; Cell Line ; Down-Regulation ; Epithelial Cells/metabolism ; Epithelial Cells/drug effects

LCZ696, an angiotensin receptor-neprilysin inhibitor, ameliorates epithelial-mesenchymal transition of peritoneal mesothelial cells and M2 macrophage polarization.

Authors: Hu Y; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China., Zhou C; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China., Zhong Q; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China., Li X; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China., Li J; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China., Shi Y; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China., Ma X; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China., Jiang D; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China., Wang Y; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China., Zhuang S; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.; Department of Medicine, Rhode Island Hospital and Alpert Medical School, Brown University, Providence, RI, USA., Liu N; Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.

Source: Renal failure [Ren Fail] 2024 Dec; Vol. 46 (2), pp. 2392849. Date of Electronic Publication: 2024 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition*/drug effects , Valsartan*/pharmacology , Biphenyl Compounds*/pharmacology , Angiotensin Receptor Antagonists*/pharmacology , Peritoneal Fibrosis*/metabolism , Peritoneal Fibrosis*/pathology , Peritoneal Fibrosis*/prevention & control , Tetrazoles*/pharmacology , Macrophages*/drug effects , Macrophages*/metabolism, Mice ; Animals ; Humans ; Aminobutyrates/pharmacology ; RAW 264.7 Cells ; Disease Models, Animal ; Drug Combinations ; Neprilysin/antagonists & inhibitors ; Neprilysin/metabolism ; Male ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Transforming Growth Factor beta1/metabolism ; STAT6 Transcription Factor/metabolism ; Peritoneum/pathology ; Peritoneum/cytology ; Peritoneum/drug effects ; Signal Transduction/drug effects ; Mice, Inbred C57BL

Adaptation to acidic conditions that mimic the tumor microenvironment, downregulates miR-193b-3p, and induces EMT via TGFβ2 in A549 cells.

Authors: Higashi S; Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Yamakuchi M; Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Hashinokuchi H; Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Takenouchi K; Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Tabaru A; Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Oyama Y; Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Fujisaki C; Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Tanoue K; Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan., Hashiguchi T; Department of Laboratory and Vascular Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

Source: PloS one [PLoS One] 2025 Feb 24; Vol. 20 (2), pp. e0318811. Date of Electronic Publication: 2025 Feb 24 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: MicroRNAs*/genetics , MicroRNAs*/metabolism , Epithelial-Mesenchymal Transition*/genetics , Tumor Microenvironment*/genetics , Transforming Growth Factor beta2*/metabolism , Transforming Growth Factor beta2*/genetics , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism, Humans ; A549 Cells ; Down-Regulation ; Gene Expression Regulation, Neoplastic ; Cell Movement ; Hydrogen-Ion Concentration