Deficiency in nucleoside diphosphate kinase B leads to endothelial activation of the hexosamine biosynthesis pathway and cardiac dysfunction.

Authors: Shao F; Experimental Pharmacology Mannheim, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167, Mannheim, Germany., Wieland J; Experimental Pharmacology Mannheim, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167, Mannheim, Germany.; DZHK (German Center of Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany., Wang Y; Experimental Pharmacology Mannheim, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167, Mannheim, Germany., Keles M; Department of Cardiovascular Physiology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.; DZHK (German Center of Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany., Meng Z; DZHK (German Center of Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany.; First Department of Medicine, Faculty of Medicine, University Medical Centre Mannheim (UMM), University of Heidelberg, 68167 Mannheim, Germany., Lomada S; Experimental Pharmacology Mannheim, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167, Mannheim, Germany.; DZHK (German Center of Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany., Qin M; Experimental Pharmacology Mannheim, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167, Mannheim, Germany., Leiss V; Department of Pharmacology, Experimental Therapy and Toxicology, University of Tübingen, 72074 Tübingen, Germany., Martin-Garrido A; Department of Cardiovascular Physiology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany., Fuhrmann M; Department of Cardiovascular Physiology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany., Qiu Y; Experimental Pharmacology Mannheim, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167, Mannheim, Germany., Trogisch FA; Department of Cardiovascular Physiology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.; DZHK (German Center of Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany., Vettel C; Experimental Pharmacology Mannheim, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167, Mannheim, Germany.; DZHK (German Center of Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany., Heineke J; Department of Cardiovascular Physiology, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.; DZHK (German Center of Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany., Feng Y; Experimental Pharmacology Mannheim, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13-17, 68167, Mannheim, Germany. Yuxi.feng@medma.uni-heidelberg.de.

Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2025 Feb 21; Vol. 24 (1), pp. 84. Date of Electronic Publication: 2025 Feb 21.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE

MeSH Terms: Hexosamines*/biosynthesis , Endothelial Cells*/enzymology , Myocytes, Cardiac*/enzymology , Myocytes, Cardiac*/pathology , NM23 Nucleoside Diphosphate Kinases*/deficiency , NM23 Nucleoside Diphosphate Kinases*/genetics , Ventricular Function, Left* , Ventricular Dysfunction, Left*/enzymology , Ventricular Dysfunction, Left*/physiopathology , Ventricular Dysfunction, Left*/genetics , Ventricular Dysfunction, Left*/diagnostic imaging , Hypertrophy, Left Ventricular*/enzymology , Hypertrophy, Left Ventricular*/physiopathology , Hypertrophy, Left Ventricular*/genetics, Animals ; Mice, Knockout ; Cells, Cultured ; Myocardial Contraction ; Disease Models, Animal ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism ; Male ; Phosphorylation ; Mice, Inbred C57BL ; Signal Transduction ; Calcium-Binding Proteins/metabolism ; Mice ; Ventricular Remodeling

NME6 as a potential biomarker and therapeutic target involved in immune infiltration for lung adenocarcinoma.

Authors: Luo L; Department of Critical Care Medicine, Wenjiang District People's Hospital of Chengdu, Chengdu, Sichuan, China.; Department of Critical Care Medicine, Wenjiang District People's Hospital of Chengdu, Chengdu, Sichuan, China., Li Y; Department of Respiratory and Critical Care Medicine, Wenjiang District People's Hospital of Chengdu, Chengdu, Sichuan, China.; Department of Critical Care Medicine, Wenjiang District People's Hospital of Chengdu, Chengdu, Sichuan, China., Zhang L; Department of Respiratory and Critical Care Medicine, Wenjiang District People's Hospital of Chengdu, Chengdu, Sichuan, China.; Department of Critical Care Medicine, Wenjiang District People's Hospital of Chengdu, Chengdu, Sichuan, China., Yang L; Prevention and Treatment Center, Teaching Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

Source: Technology and health care : official journal of the European Society for Engineering and Medicine [Technol Health Care] 2024; Vol. 32 (4), pp. 2277-2291.

Publication Type: Journal Article

Journal Info: Publisher: IOS Press Country of Publication: Netherlands NLM ID: 9314590 Publication Model: Print Cited Medium: Internet ISSN: 1878-7401 (Electronic) Linking ISSN: 09287329 NLM ISO Abbreviation: Technol Health Care Subsets: MEDLINE

MeSH Terms: Adenocarcinoma of Lung*/immunology , Adenocarcinoma of Lung*/genetics , Adenocarcinoma of Lung*/pathology , Biomarkers, Tumor*/analysis , Biomarkers, Tumor*/genetics , Lung Neoplasms*/immunology , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , NM23 Nucleoside Diphosphate Kinases*/analysis , NM23 Nucleoside Diphosphate Kinases*/genetics, Humans ; Prognosis

NME5 frameshift variant in Alaskan Malamutes with primary ciliary dyskinesia.

Authors: Anderegg L; Institute of Genetics, Vetsuisse Faculty, University of Bern,Bern, Switzerland., Im Hof Gut M; Kleintierpraxis Laupeneck, Bern, Switzerland., Hetzel U; Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland., Howerth EW; Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens GA, United States of America., Leuthard F; Institute of Genetics, Vetsuisse Faculty, University of Bern,Bern, Switzerland., Kyöstilä K; Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland.; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland., Lohi H; Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland.; Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland., Pettitt L; Kennel Club Genetics Centre, Animal Health Trust, Newmarket, Suffolk CB UU, United Kingdom., Mellersh C; Kennel Club Genetics Centre, Animal Health Trust, Newmarket, Suffolk CB UU, United Kingdom., Minor KM; Department of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, MN, United States of America., Mickelson JR; Department of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, MN, United States of America., Batcher K; Department of Population Health and Reproduction, University of California-Davis, Davis, CA, United States of America., Bannasch D; Department of Population Health and Reproduction, University of California-Davis, Davis, CA, United States of America., Jagannathan V; Institute of Genetics, Vetsuisse Faculty, University of Bern,Bern, Switzerland., Leeb T; Institute of Genetics, Vetsuisse Faculty, University of Bern,Bern, Switzerland.

Source: PLoS genetics [PLoS Genet] 2019 Sep 03; Vol. 15 (9), pp. e1008378. Date of Electronic Publication: 2019 Sep 03 (Print Publication: 2019).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

MeSH Terms: Ciliary Motility Disorders/*genetics , NM23 Nucleoside Diphosphate Kinases/*genetics, Animals ; Breeding ; Cilia/genetics ; Ciliary Motility Disorders/physiopathology ; Dogs/genetics ; Female ; Frameshift Mutation/genetics ; Genetic Linkage/genetics ; Genetic Testing ; Genotype ; Humans ; Male ; Mutation/genetics ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Phenotype ; Whole Genome Sequencing

Mix and match of the tumor metastasis suppressor Nm23 protein isoforms in vitro and in vivo.

Authors: Potel CM; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, The Netherlands.; Netherlands Proteomics Centre, Utrecht, The Netherlands., Fasci D; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, The Netherlands.; Netherlands Proteomics Centre, Utrecht, The Netherlands., Heck AJR; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, The Netherlands.; Netherlands Proteomics Centre, Utrecht, The Netherlands.

Source: The FEBS journal [FEBS J] 2018 Aug; Vol. 285 (15), pp. 2856-2868. Date of Electronic Publication: 2018 Jun 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

MeSH Terms: Mass Spectrometry/*methods , NM23 Nucleoside Diphosphate Kinases/*isolation & purification, HEK293 Cells ; Humans ; NM23 Nucleoside Diphosphate Kinases/analysis ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Phosphorylation ; Protein Isoforms/analysis ; Protein Isoforms/isolation & purification ; Protein Isoforms/metabolism

The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor.

Authors: Lacombe ML; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris, France., Lamarche F; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France., De Wever O; Laboratory of Experimental Cancer Research, Department of Human Structure and Repair, Cancer Research Institute Ghent (CRIG), Ghent University, Ghent, Belgium., Padilla-Benavides T; Molecular Biology and Biochemistry Department, Wesleyan University, Middletown, USA., Carlson A; Molecular Biology and Biochemistry Department, Wesleyan University, Middletown, USA., Khan I; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, USA., Huna A; Cancer Research Center of Lyon, INSERM U1052, CNRS UMR 5286, Léon Bérard Center, Lyon University, Lyon, France., Vacher S; Unit of Pharmacogenetics, Department of Genetics, Curie Institute, Paris, France., Calmel C; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris, France., Desbourdes C; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France., Cottet-Rousselle C; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France., Hininger-Favier I; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France., Attia S; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France., Nawrocki-Raby B; Reims Champagne Ardenne University, INSERM, P3Cell UMR-S 1250, SFR CAP-SANTE, Reims, France., Raingeaud J; INSERM U1279, Gustave Roussy Institute, Villejuif, France., Machon C; Cancer Research Center of Lyon, INSERM U1052, CNRS UMR 5286, Léon Bérard Center, Lyon University, Lyon, France., Guitton J; Cancer Research Center of Lyon, INSERM U1052, CNRS UMR 5286, Léon Bérard Center, Lyon University, Lyon, France., Le Gall M; Proteomics Platform 3P5, Paris University, Cochin Institute, INSERM, U1016, CNRS, UMR8104, Paris, France., Clary G; Proteomics Platform 3P5, Paris University, Cochin Institute, INSERM, U1016, CNRS, UMR8104, Paris, France., Broussard C; Proteomics Platform 3P5, Paris University, Cochin Institute, INSERM, U1016, CNRS, UMR8104, Paris, France., Chafey P; Proteomics Platform 3P5, Paris University, Cochin Institute, INSERM, U1016, CNRS, UMR8104, Paris, France., Thérond P; AP-HP, CHU Bicêtre, Laboratory of Biochemistry, Le Kremlin-Bicêtre Hospital, Le Kremlin-Bicêtre, France.; EA7537, Paris Saclay University, Châtenay-Malabry, France., Bernard D; Cancer Research Center of Lyon, INSERM U1052, CNRS UMR 5286, Léon Bérard Center, Lyon University, Lyon, France., Fontaine E; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France., Tokarska-Schlattner M; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), and SFR Environmental and Systems Biology (BEeSy), Grenoble, France., Steeg P; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, USA., Bièche I; Unit of Pharmacogenetics, Department of Genetics, Curie Institute, Paris, France., Schlattner U; Université Grenoble Alpes, INSERM U1055, Laboratory of Fundamental and Applied Bioenergetics (LBFA), Institut Universitaire de France (IUF), Grenoble, France. uwe.schlattner@univ-grenoble-alpes.fr., Boissan M; Sorbonne Université, Inserm, Centre de Recherche Saint-Antoine, CRSA, Paris, France. mathieu.boissan@inserm.fr.; AP-HP, Laboratory of Biochemistry and Hormonology, Tenon Hospital, Paris, France. mathieu.boissan@inserm.fr.

Source: BMC biology [BMC Biol] 2021 Oct 21; Vol. 19 (1), pp. 228. Date of Electronic Publication: 2021 Oct 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007 (Electronic) Linking ISSN: 17417007 NLM ISO Abbreviation: BMC Biol Subsets: MEDLINE

MeSH Terms: Neoplasms*/genetics , Neoplasms*/metabolism , Nucleoside-Diphosphate Kinase*/genetics , Nucleoside-Diphosphate Kinase*/metabolism, Animals ; Intracellular Membranes ; Mice ; Mitochondria ; NM23 Nucleoside Diphosphate Kinases/genetics ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Nucleoside Diphosphate Kinase D/metabolism

Meta-Analysis of the Relationship between NM23 Expression to Gastric Cancer Risk and Clinical Features.

Authors: Fang M; Department of Clinical Laboratory, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China., Tao Y; Department of Clinical Laboratory, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China., Liu Z; Department of Clinical Laboratory, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China., Huang H; Department of Clinical Laboratory, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China., Lao M; Department of Clinical Laboratory, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China., Huang L; Department of Clinical Laboratory, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China., Zhu B; Department of Clinical Laboratory, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Source: BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 8047183. Date of Electronic Publication: 2017 Mar 16.

Publication Type: Journal Article; Meta-Analysis; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101600173 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2314-6141 (Electronic) NLM ISO Abbreviation: Biomed Res Int Subsets: MEDLINE

MeSH Terms: Prognosis*, Biomarkers, Tumor/*biosynthesis , NM23 Nucleoside Diphosphate Kinases/*biosynthesis , Stomach Neoplasms/*genetics, Biomarkers, Tumor/genetics ; Disease Progression ; Disease-Free Survival ; Gene Expression Regulation, Neoplastic ; Humans ; NM23 Nucleoside Diphosphate Kinases/genetics ; Neoplasm Staging ; Risk Factors ; Stomach Neoplasms/pathology

Role of Interaction and Nucleoside Diphosphate Kinase B in Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Function by cAMP-Dependent Protein Kinase A.

Authors: Borthwick LA; Academic Unit of Respiratory Medicine, Department of Infection and Immunity, The University of Sheffield, The Medical School, Sheffield, S10 2RX, United Kingdom., Kerbiriou M; Academic Unit of Respiratory Medicine, Department of Infection and Immunity, The University of Sheffield, The Medical School, Sheffield, S10 2RX, United Kingdom., Taylor CJ; Academic Unit of Child Health, University of Sheffield, Stephenson Wing, Sheffield Children's Hospital, Sheffield, S10 2TH, United Kingdom., Cozza G; Department of Biomedical Sciences, University of Padova, Via Ugo Bassi 58/B 35131, Padova, Italy., Lascu I; University of Bordeaux, France, and Institut de Biochimie et Genetique Cellulaires, Centre Nationale de la Recherche Scientifique UMR 5095, 33077, Bordeaux, France., Postel EH; Robert Wood Johnson Medical School, UMDNJ, New Brunswick, New Jersey, United States of America., Cassidy D; Medical Research Institute/CVS Diabetes Lung, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, United Kingdom., Trouvé P; Inserm UMR 1078, Génétique, Génomique Fonctionnelle et Biotechnologies, 46 rue Félix Le Dantec, 29218, Brest Cedex2, France., Mehta A; Medical Research Institute/CVS Diabetes Lung, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, United Kingdom., Robson L; Department of Biomedical Science, The University of Sheffield, Western Bank, Sheffield, S10 2TN, United Kingdom., Muimo R; Academic Unit of Respiratory Medicine, Department of Infection and Immunity, The University of Sheffield, The Medical School, Sheffield, S10 2RX, United Kingdom.

Source: PloS one [PLoS One] 2016 Mar 07; Vol. 11 (3), pp. e0149097. Date of Electronic Publication: 2016 Mar 07 (Print Publication: 2016).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Cyclic AMP-Dependent Protein Kinases/*metabolism , Cystic Fibrosis Transmembrane Conductance Regulator/*metabolism , NM23 Nucleoside Diphosphate Kinases/*metabolism, Amino Acid Sequence ; Animals ; Binding Sites ; Cell Line ; Cell Membrane/metabolism ; Cell Polarity ; Cyclic AMP/metabolism ; Cystic Fibrosis Transmembrane Conductance Regulator/chemistry ; Cytosol/metabolism ; Epithelial Cells/cytology ; Humans ; Models, Molecular ; Molecular Sequence Data ; NM23 Nucleoside Diphosphate Kinases/chemistry ; Protein Binding ; Protein Structure, Tertiary ; Protein Transport ; Respiratory System/cytology ; Young Adult

Metastasis suppressor NME1 regulates melanoma cell morphology, self-adhesion and motility via induction of fibronectin expression.

Authors: Novak M; Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, School of Medicine, University of Maryland-Baltimore, Baltimore, MD, USA., Leonard MK; Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, School of Medicine, University of Maryland-Baltimore, Baltimore, MD, USA., Yang XH; Department of Molecular and Biomedical Pharmacology, College of Medicine, University of Kentucky, Lexington, KY, USA., Kowluru A; Department of Pharmaceutical Sciences, John D. Dingell VA Medical Center, Wayne State University, Detroit, MI, USA., Belkin AM; Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, School of Medicine, University of Maryland-Baltimore, Baltimore, MD, USA.; Center for Vascular and Inflammatory Disease, School of Medicine, University of Maryland-Baltimore, Baltimore, MD, USA., Kaetzel DM; Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, School of Medicine, University of Maryland-Baltimore, Baltimore, MD, USA.

Source: Experimental dermatology [Exp Dermatol] 2015 Jun; Vol. 24 (6), pp. 455-61. Date of Electronic Publication: 2015 Apr 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9301549 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0625 (Electronic) Linking ISSN: 09066705 NLM ISO Abbreviation: Exp Dermatol Subsets: MEDLINE

MeSH Terms: Cell Adhesion/*physiology , Cell Movement/*physiology , Fibronectins/*physiology , Melanoma/*pathology , NM23 Nucleoside Diphosphate Kinases/*physiology , Skin Neoplasms/*pathology, Cell Line, Tumor ; Disease Progression ; Extracellular Matrix/pathology ; Extracellular Matrix/physiology ; Fibronectins/genetics ; Gene Expression Regulation, Neoplastic/physiology ; Humans ; In Vitro Techniques ; Melanoma/physiopathology ; NM23 Nucleoside Diphosphate Kinases/genetics ; Neoplasm Metastasis/pathology ; Neoplasm Metastasis/physiopathology ; RNA, Messenger/genetics ; RNA, Messenger/physiology ; Signal Transduction/physiology ; Skin Neoplasms/physiopathology

MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naïve state.

Authors: Smagghe BJ; Minerva Biotechnologies, Waltham, Massachusetts, United States of America., Stewart AK, Carter MG, Shelton LM, Bernier KJ, Hartman EJ, Calhoun AK, Hatziioannou VM, Lillacci G, Kirk BA, DiNardo BA, Kosik KS, Bamdad C

Source: PloS one [PLoS One] 2013; Vol. 8 (3), pp. e58601. Date of Electronic Publication: 2013 Mar 07.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: NM23 Nucleoside Diphosphate Kinases/*pharmacology , Stem Cells/*drug effects, Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/metabolism ; Binding, Competitive ; Biomarkers/metabolism ; Cell Differentiation ; Cells, Cultured ; Culture Media, Conditioned/pharmacology ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/drug effects ; Embryonic Stem Cells/metabolism ; Fibroblast Growth Factor 2/pharmacology ; Fibroblasts/metabolism ; Humans ; Induced Pluripotent Stem Cells/cytology ; Induced Pluripotent Stem Cells/drug effects ; Induced Pluripotent Stem Cells/metabolism ; Ligands ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Mucin-1/immunology ; Mucin-1/metabolism ; NM23 Nucleoside Diphosphate Kinases/chemistry ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Protein Binding/drug effects ; Protein Multimerization ; Stem Cells/cytology ; Stem Cells/metabolism

Notch signaling during development requires the function of awd, the Drosophila homolog of human metastasis suppressor gene Nm23.

Authors: Ignesti M, Barraco M, Nallamothu G, Woolworth JA, Duchi S, Gargiulo G, Cavaliere V; Dipartimento di Farmacia e Biotecnologie, Alma Mater Studiorum Università di Bologna, Via Selmi, 3, Bologna 40126, Italy. valeria.cavaliere@unibo.it., Hsu T

Source: BMC biology [BMC Biol] 2014 Feb 14; Vol. 12, pp. 12. Date of Electronic Publication: 2014 Feb 14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007 (Electronic) Linking ISSN: 17417007 NLM ISO Abbreviation: BMC Biol Subsets: MEDLINE

MeSH Terms: Sequence Homology, Amino Acid* , Signal Transduction*, Drosophila Proteins/*metabolism , Drosophila melanogaster/*metabolism , NM23 Nucleoside Diphosphate Kinases/*genetics , Nucleoside-Diphosphate Kinase/*metabolism , Receptors, Notch/*metabolism, Animals ; Cell Proliferation ; Clone Cells ; Cytoplasmic Vesicles ; Drosophila melanogaster/genetics ; Drosophila melanogaster/growth & development ; Endocytosis ; Endosomes/metabolism ; Female ; Gene Expression Regulation, Developmental ; Humans ; Imaginal Discs/cytology ; Larva/growth & development ; Larva/metabolism ; Mutation/genetics ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Neoplasm Metastasis ; Ovarian Follicle/cytology ; Ovarian Follicle/metabolism ; Protein Transport ; Wings, Animal/cytology ; Wings, Animal/metabolism ; rab5 GTP-Binding Proteins/metabolism

Nme gene family evolutionary history reveals pre-metazoan origins and high conservation between humans and the sea anemone, Nematostella vectensis.

Authors: Desvignes T; UMR 6632/IFR48, Université de Provence Aix Marseille 1/CNRS, F-13000, Marseille, France., Pontarotti P, Bobe J

Source: PloS one [PLoS One] 2010 Nov 11; Vol. 5 (11), pp. e15506. Date of Electronic Publication: 2010 Nov 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Evolution, Molecular*, Multigene Family/*genetics , NM23 Nucleoside Diphosphate Kinases/*genetics , Sea Anemones/*genetics, Animals ; Chromosome Mapping ; Humans ; NM23 Nucleoside Diphosphate Kinases/classification ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Phylogeny ; Sea Anemones/metabolism ; Species Specificity

A high nuclear nm23-H1 expression is associated with a better prognosis in elderly patients with laryngeal carcinoma.

Authors: Lionello M; Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy., Blandamura S, Lovato A, Franchella S, Giacomelli L, Ottaviano G, Stellini E, Staffieri A, Marioni G

Source: Acta oto-laryngologica [Acta Otolaryngol] 2013 Aug; Vol. 133 (8), pp. 874-80. Date of Electronic Publication: 2013 Jun 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 0370354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1651-2251 (Electronic) Linking ISSN: 00016489 NLM ISO Abbreviation: Acta Otolaryngol Subsets: MEDLINE

MeSH Terms: Biomarkers, Tumor/*biosynthesis , Carcinoma/*metabolism , Laryngeal Neoplasms/*metabolism , NM23 Nucleoside Diphosphate Kinases/*biosynthesis , Neoplasm Recurrence, Local/*metabolism, Aged ; Aged, 80 and over ; Carcinoma/pathology ; Female ; Humans ; Laryngeal Neoplasms/pathology ; Male ; Multivariate Analysis ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Prognosis ; Retrospective Studies

Diva/BclB regulates differentiation by inhibiting NDPKB/Nm23H2-mediated neuronal differentiation in PC-12 cells.

Authors: Lim JQ; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, 117597, Singapore., Lu J, He BP

Source: BMC neuroscience [BMC Neurosci] 2012 Oct 11; Vol. 13, pp. 123. Date of Electronic Publication: 2012 Oct 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100966986 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2202 (Electronic) Linking ISSN: 14712202 NLM ISO Abbreviation: BMC Neurosci Subsets: MEDLINE

MeSH Terms: Cell Differentiation/*physiology , NM23 Nucleoside Diphosphate Kinases/*antagonists & inhibitors , Neurons/*cytology , Nucleoside-Diphosphate Kinase/*antagonists & inhibitors , Proto-Oncogene Proteins c-bcl-2/*physiology, Animals ; Cell Cycle/physiology ; Gene Expression Regulation/physiology ; NM23 Nucleoside Diphosphate Kinases/biosynthesis ; Neurites/metabolism ; Neurons/metabolism ; Nucleoside-Diphosphate Kinase/biosynthesis ; PC12 Cells ; Protein Transport/physiology ; Proto-Oncogene Proteins c-bcl-2/biosynthesis ; Rats ; Signal Transduction/physiology ; Tubulin/metabolism

Identification of NME5 as a contributor to innate resistance to gemcitabine in pancreatic cancer cells.

Authors: Li F; Jiangsu Center of Drug Screening, China Pharmaceutical University, Nanjing, Jiangsu Province, China., Hu G, Jiang Z, Guo J, Wang K, Ouyang K, Wen D, Zhu M, Liang J, Qin X, Zhang L

Source: The FEBS journal [FEBS J] 2012 Apr; Vol. 279 (7), pp. 1261-73. Date of Electronic Publication: 2012 Mar 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

MeSH Terms: Antimetabolites, Antineoplastic/*therapeutic use , Deoxycytidine/*analogs & derivatives , Drug Resistance, Neoplasm/*physiology , NM23 Nucleoside Diphosphate Kinases/*metabolism , Pancreatic Neoplasms/*drug therapy , Pancreatic Neoplasms/*physiopathology, Animals ; Apoptosis/physiology ; Cell Cycle/physiology ; Cell Cycle Checkpoints ; Cell Line, Tumor ; Deoxycytidine/therapeutic use ; Down-Regulation ; Gene Knockdown Techniques ; Humans ; Mice ; Mice, SCID ; NF-kappa B/genetics ; NF-kappa B/metabolism ; NM23 Nucleoside Diphosphate Kinases/genetics ; Neoplasm Transplantation ; Gemcitabine

The nucleoside diphosphate kinase gene Nme3 acts as quantitative trait locus promoting non-Mendelian inheritance.

Authors: Bauer H; Department of Developmental Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany. herrmann@molgen.mpg.de, Schindler S, Charron Y, Willert J, Kusecek B, Herrmann BG

Source: PLoS genetics [PLoS Genet] 2012; Vol. 8 (3), pp. e1002567. Date of Electronic Publication: 2012 Mar 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

MeSH Terms: Quantitative Trait Loci*/genetics , rho GTP-Binding Proteins*/genetics , rho GTP-Binding Proteins*/metabolism, NM23 Nucleoside Diphosphate Kinases/*genetics , Sperm Motility/*genetics , t-Complex Genome Region/*genetics, Amino Acid Sequence ; Animals ; Heredity ; Male ; Mice ; Mice, Transgenic ; Molecular Sequence Data ; Mutation ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Phenotype ; Protein Kinases/genetics ; Protein Kinases/metabolism ; Spermatozoa/physiology

The anti-metastatic nm23-1 gene is needed for the final step of mammary duct maturation of the mouse nipple.

Authors: Deplagne C; Unité U1035, INSERM, Bordeaux, France., Peuchant E, Moranvillier I, Dubus P, Dabernat S

Source: PloS one [PLoS One] 2011 Apr 07; Vol. 6 (4), pp. e18645. Date of Electronic Publication: 2011 Apr 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Mammary Glands, Animal/*metabolism , NM23 Nucleoside Diphosphate Kinases/*metabolism , Nipples/*metabolism, Animals ; Apoptosis/genetics ; Apoptosis/physiology ; Blotting, Western ; Cell Proliferation ; Epithelium/metabolism ; Female ; Humans ; Lactation/genetics ; Lactation/physiology ; Mice ; Mice, Knockout ; Mice, Transgenic ; NM23 Nucleoside Diphosphate Kinases/genetics ; Polymerase Chain Reaction

Comparative evaluation of nm23 and p16 expression as biomarkers of high-risk human papillomavirus infection and cervical intraepithelial neoplasia 2(+) lesions of the uterine cervix.

Authors: Benevolo M; Departments of Pathology Epidemiology Scientific Direction Oncologic Gynecology, Regina Elena Cancer Institute, Rome, Italy. benevolo@ifo.it, Terrenato I, Mottolese M, Marandino F, Muti P, Carosi M, Rollo F, Ronchetti L, Mariani L, Vocaturo G, Vocaturo A

Source: Histopathology [Histopathology] 2010 Oct; Vol. 57 (4), pp. 580-6.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 7704136 Publication Model: Print Cited Medium: Internet ISSN: 1365-2559 (Electronic) Linking ISSN: 03090167 NLM ISO Abbreviation: Histopathology Subsets: MEDLINE

MeSH Terms: Biomarkers, Tumor/*analysis , NM23 Nucleoside Diphosphate Kinases/*analysis , Neoplasm Proteins/*analysis , Uterine Cervical Neoplasms/*pathology , Uterine Cervical Dysplasia/*pathology, Adolescent ; Adult ; Aged ; Biomarkers, Tumor/metabolism ; Cyclin-Dependent Kinase Inhibitor p16 ; Female ; Humans ; Immunohistochemistry ; Middle Aged ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Neoplasm Proteins/metabolism ; Papillomavirus Infections/complications ; Polymerase Chain Reaction ; Risk Factors ; Sensitivity and Specificity ; Uterine Cervical Neoplasms/virology ; Young Adult ; Uterine Cervical Dysplasia/virology

Nme protein family evolutionary history, a vertebrate perspective.

Authors: Desvignes T; INRA, UR1037 SCRIBE, IFR140, Ouest-Genopole, F-35000 Rennes, France. thomas.desvignes@rennes.inra.fr, Pontarotti P, Fauvel C, Bobe J

Source: BMC evolutionary biology [BMC Evol Biol] 2009 Oct 23; Vol. 9, pp. 256. Date of Electronic Publication: 2009 Oct 23.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100966975 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2148 (Electronic) Linking ISSN: 14712148 NLM ISO Abbreviation: BMC Evol Biol Subsets: MEDLINE

MeSH Terms: Evolution, Molecular*, NM23 Nucleoside Diphosphate Kinases/*genetics , Vertebrates/*genetics, Amino Acid Sequence ; Animals ; Conserved Sequence ; Humans ; Molecular Sequence Data ; NM23 Nucleoside Diphosphate Kinases/chemistry ; Phylogeny ; Sequence Alignment

Nanoparticle delivery of anti-metastatic NM23-H1 gene improves chemotherapy in a mouse tumor model.

Authors: Li Z; Cancer Research Institute, Central South University, Changsha, Hunan, The People's Republic of China., Xiang J, Zhang W, Fan S, Wu M, Li X, Li G

Source: Cancer gene therapy [Cancer Gene Ther] 2009 May; Vol. 16 (5), pp. 423-9. Date of Electronic Publication: 2008 Dec 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5500 (Electronic) Linking ISSN: 09291903 NLM ISO Abbreviation: Cancer Gene Ther Subsets: MEDLINE

MeSH Terms: Gene Transfer Techniques* , Genetic Therapy* , Genetic Vectors*/administration & dosage , Genetic Vectors*/toxicity, Antineoplastic Agents/*pharmacology , NM23 Nucleoside Diphosphate Kinases/*administration & dosage , Nanoparticles/*therapeutic use, Animals ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Disease Models, Animal ; Gene Expression Regulation, Neoplastic ; Inhibitor of Apoptosis Proteins ; Mice ; Mice, Inbred C57BL ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Neoplasm Metastasis ; Survivin ; Zebrafish Proteins

Clinical significance of altered nm23-H1, EGFR, RB and p53 expression in bilharzial bladder cancer.

Authors: Khaled HM; Pathology Department, National Cancer Institute, Cairo University, Cairo, Egypt. khaled@internetegypt.com, Bahnassy AA, Raafat AA, Zekri AR, Madboul MS, Mokhtar NM

Source: BMC cancer [BMC Cancer] 2009 Jan 26; Vol. 9, pp. 32. Date of Electronic Publication: 2009 Jan 26.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

MeSH Terms: Biomarkers, Tumor/*biosynthesis , ErbB Receptors/*biosynthesis , NM23 Nucleoside Diphosphate Kinases/*biosynthesis , Retinoblastoma Protein/*biosynthesis , Tumor Suppressor Protein p53/*biosynthesis , Urinary Bladder Neoplasms/*metabolism, Adult ; Aged ; Biomarkers, Tumor/genetics ; ErbB Receptors/genetics ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; NM23 Nucleoside Diphosphate Kinases/genetics ; RNA, Neoplasm/genetics ; RNA, Neoplasm/metabolism ; Schistosomiasis/genetics ; Schistosomiasis/metabolism ; Schistosomiasis/pathology ; Survival Rate ; Tumor Suppressor Protein p53/genetics ; Urinary Bladder Neoplasms/genetics ; Urinary Bladder Neoplasms/parasitology ; Urinary Bladder Neoplasms/pathology