How animal ethics committees make decisions - a scoping review of empirical studies.

Autores: Milford A; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland., De Clercq E; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland., Louis-Maerten E; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland., Geneviève LD; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland., Elger BS; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland.; Center of Legal Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Fonte: PloS one [PLoS One] 2025 Mar 17; Vol. 20 (3), pp. e0318570. Date of Electronic Publication: 2025 Mar 17 (Print Publication: 2025).

Tipo de Publicação: Journal Article; Scoping Review

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Decision Making* , Animal Experimentation*/ethics , Animal Care Committees* , Animal Welfare*/ethics, Animals

CRIME-Q-a unifying tool for critical appraisal of methodological (technical) quality, quality of reporting and risk of bias in animal research.

Autores: Andersen MS; Department of Neurosurgery, Odense University Hospital, Odense, Denmark. Mikkel.c.schou.andersen@rsyd.dk.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark. Mikkel.c.schou.andersen@rsyd.dk.; BRIDGE (Brain Research - Inter Disciplinary Guided Excellence), University of Southern Denmark, Odense, Denmark. Mikkel.c.schou.andersen@rsyd.dk., Kofoed MS; Department of Neurosurgery, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; BRIDGE (Brain Research - Inter Disciplinary Guided Excellence), University of Southern Denmark, Odense, Denmark., Paludan-Müller AS; Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark.; Centre for Evidence-Based Medicine Odense (CEBMO), Copenhagen, Denmark.; NHTA: Market Access & Health Economics Consultancy, Copenhagen, Denmark., Pedersen CB; Department of Neurosurgery, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; BRIDGE (Brain Research - Inter Disciplinary Guided Excellence), University of Southern Denmark, Odense, Denmark., Mathiesen T; Department of Neurosurgery, Rigshospitalet, Copenhagen, Denmark.; Copenhagen University, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Mawrin C; Department of Neuropathology, Otto-Von-Guericke University, Magdeburg, Germany., Olsen BB; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.; Department of Surgical Pathology, Zealand University Hospital, Roskilde, Denmark., Halle B; Department of Neurosurgery, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; BRIDGE (Brain Research - Inter Disciplinary Guided Excellence), University of Southern Denmark, Odense, Denmark., Poulsen FR; Department of Neurosurgery, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; BRIDGE (Brain Research - Inter Disciplinary Guided Excellence), University of Southern Denmark, Odense, Denmark.

Fonte: BMC medical research methodology [BMC Med Res Methodol] 2024 Dec 19; Vol. 24 (1), pp. 306. Date of Electronic Publication: 2024 Dec 19.

Tipo de Publicação: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968545 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2288 (Electronic) Linking ISSN: 14712288 NLM ISO Abbreviation: BMC Med Res Methodol Subsets: MEDLINE

MeSH Terms: Animal Experimentation*/standards , Bias* , Checklist*/methods , Checklist*/standards , Research Design*/standards, Animals ; Humans

Beyond Anthropocentrism: The Moral and Strategic Philosophy behind Russell and Burch's 3Rs in Animal Experimentation.

Autores: Müller ND; University of Basel, Philosophical Seminar, Steinengraben 5, Basel, 4051, Switzerland. nicodario.mueller@unibas.ch.

Fonte: Science and engineering ethics [Sci Eng Ethics] 2024 Sep 11; Vol. 30 (5), pp. 44. Date of Electronic Publication: 2024 Sep 11.

Tipo de Publicação: Journal Article; Historical Article

Journal Info: Publisher: Opragen Publications Country of Publication: England NLM ID: 9516228 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-5546 (Electronic) Linking ISSN: 13533452 NLM ISO Abbreviation: Sci Eng Ethics Subsets: MEDLINE

MeSH Terms: Animal Welfare*/ethics , Animal Experimentation*/ethics , Ethics, Research* , Philosophy* , Morals*, Animals ; Humans

Challenges and opportunities of translating animal research into human trials in Ethiopia.

Autores: Abrhaley A; Department of Biomedical Sciences, College of Veterinary Medicine and Animal Sciences, University of Gondar, P.O. Box: 196, Gondar, Ethiopia. abrhaleyaskivet2015@gmail.com.; Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa University, P.O. Box 9086, Addis Ababa, Ethiopia. abrhaleyaskivet2015@gmail.com., Giday M; Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa University, P.O. Box 9086, Addis Ababa, Ethiopia.; Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia., Hailu A; Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa University, P.O. Box 9086, Addis Ababa, Ethiopia.; Department of Microbiology, Immunology, and Parasitology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Fonte: BMC medical research methodology [BMC Med Res Methodol] 2024 Sep 19; Vol. 24 (1), pp. 211. Date of Electronic Publication: 2024 Sep 19.

Tipo de Publicação: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968545 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2288 (Electronic) Linking ISSN: 14712288 NLM ISO Abbreviation: BMC Med Res Methodol Subsets: MEDLINE

MeSH Terms: Translational Research, Biomedical*/methods , Clinical Trials as Topic*/methods , Clinical Trials as Topic*/statistics & numerical data , Animal Experimentation*/statistics & numerical data, Ethiopia ; Humans ; Animals ; Qualitative Research ; Reproducibility of Results ; Research Personnel/statistics & numerical data

Eleven quick tips to unlock the power of in vivo data science.

Autores: Kieran, Troy J.¹ (AUTHOR) tkieran@cdc.gov, Maines, Taronna R.¹ (AUTHOR), Belser, Jessica A.¹ (AUTHOR) jbelser@cdc.gov

Fonte: PLoS Computational Biology. 4/17/2025, Vol. 21 Issue 4, p1-9. 9p.

Termos do assunto: *LIFE sciences, *ANIMAL experimentation, *INTERNET forums, *DATA science, *RECORDS management, *BODY temperature, *BODY temperature regulation

Drug-induced cytotoxicity prediction in muscle cells, an application of the Cell Painting assay.

Autores: Lambert, Roman^1,2 (AUTHOR) r.lambert4@universityofgalway.ie, Serrano Candelas, Eva² (AUTHOR), Aparicio, Pablo³ (AUTHOR), Murphy, Aisling^1,2 (AUTHOR), Gozalbes, Rafael^2,3 (AUTHOR), Fearnhead, Howard Oliver¹ (AUTHOR)

Fonte: PLoS ONE. 3/31/2025, Vol. 20 Issue 3, p1-20. 20p.

Termos do assunto: *ANIMAL experimentation, *CYTOTOXINS, *PHENOTYPIC plasticity, *MUSCLE cells, *CANCER cells

Professional quality of life in animal research personnel is linked to retention & job satisfaction: A mixed-methods cross-sectional survey on compassion fatigue in the USA.

Autores: Young L; Department of Integrative Biology, University of Guelph, Guelph, Ontario, Canada.; The 3Rs Collaborative, Denver, Colorado, United States of America., Ferrara F; Consulting and Training in Animal Research, Berlin, Germany., Kelly L; University of Georgia, Athens, Georgia, United States of America., Martin T; Refinement and Enrichment Advancements Laboratory, Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America., Thompson-Iritani S; Department of Environmental and Occupational Health Sciences, Office of Research, University of Washington, Seattle, WA, United States of America., LaFollette MR; The 3Rs Collaborative, Denver, Colorado, United States of America.

Fonte: PloS one [PLoS One] 2024 Apr 16; Vol. 19 (4), pp. e0298744. Date of Electronic Publication: 2024 Apr 16 (Print Publication: 2024).

Tipo de Publicação: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Compassion Fatigue*/psychology , Animal Experimentation* , Burnout, Professional*/psychology, Humans ; Animals ; Cross-Sectional Studies ; Research Personnel ; Quality of Life ; Job Satisfaction ; Empathy ; Surveys and Questionnaires ; Personal Satisfaction

Perceptions of 3R implementation in European animal research: A systematic review, meta-analysis, and meta-synthesis of barriers and facilitators.

Autores: Louis-Maerten E; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland., Milford A; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland., Shaw DM; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland.; Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands., Geneviève LD; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland., Elger BS; Institute for Biomedical Ethics, University of Basel, Basel, Switzerland.; Faculty of Medicine, Center of Legal Medicine, University of Geneva, Geneva, Switzerland.

Fonte: PloS one [PLoS One] 2024 Mar 28; Vol. 19 (3), pp. e0300031. Date of Electronic Publication: 2024 Mar 28 (Print Publication: 2024).

Tipo de Publicação: Systematic Review; Meta-Analysis; Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One

MeSH Terms: Animal Experimentation*/ethics, Animals ; Europe ; Humans

Recommendations for measuring and standardizing light for laboratory mammals to improve welfare and reproducibility in animal research.

Autores: Lucas RJ; Centre for Biological Timing, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester, United Kingdom., Allen AE; Centre for Biological Timing, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester, United Kingdom., Brainard GC; Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America., Brown TM; Centre for Biological Timing, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester, United Kingdom., Dauchy RT; Department of Structural and Cellular Biology, Tulane University School of Medicine, Tulane, Louisiana, United States of America., Didikoglu A; Department of Neuroscience, Izmir Institute of Technology, Gülbahçe, Urla, Izmir, Turkey., Do MTH; F.M. Kirby Neurobiology Center and Department of Neurology, Boston Children's Hospital and Harvard Medical School, Center for Life Science, Boston, Massachusetts, United States of America., Gaskill BN; Novartis Institute for Biomedical Research, Cambridge, Massachusetts, United States of America., Hattar S; Section on Light and Circadian Rhythms (SLCR), National Institute of Mental Health, John Edward Porter Neuroscience Research Center, Bethesda, Maryland, United States of America., Hawkins P; RSPCA, Horsham, West Sussex, United Kingdom., Hut RA; Chronobiology Unit, Groningen Institute of Evolutionary Life Sciences, University of Groningen, Groningen, the Netherlands., McDowell RJ; Centre for Biological Timing, School of Biological Sciences, Faculty of Biology Medicine and Health, University of Manchester, Manchester, United Kingdom., Nelson RJ; Department of Neuroscience, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, West Virginia, United States of America., Prins JB; The Francis Crick Institute, London, United Kingdom.; Leiden University Medical Centre, Leiden, the Netherlands., Schmidt TM; Department of Neurobiology, Northwestern University, Evanston, Illinois, United States of America., Takahashi JS; Department of Neuroscience, Peter O'Donnell Jr Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America., Verma V; NASA Ames Research Center, Space Biosciences Division, Moffett Field, California, United States of America., Voikar V; Laboratory Animal Center and Neuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland., Wells S; The Mary Lyon Centre, MRC Harwell, Harwell Campus, Oxfordshire, United Kingdom., Peirson SN; Sleep and Circadian Neuroscience Institute (SCNi), Kavli Institute for Nanoscience Discovery, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

Fonte: PLoS biology [PLoS Biol] 2024 Mar 12; Vol. 22 (3), pp. e3002535. Date of Electronic Publication: 2024 Mar 12 (Print Publication: 2024).

Tipo de Publicação: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

MeSH Terms: Animals, Laboratory* , Animal Experimentation*, Animals ; Reproducibility of Results ; Circadian Rhythm/physiology ; Mammals

Inotodiol induces hepatocellular carcinoma apoptosis by activation of MAPK/ERK pathway.

Autores: Xing, Yushuang^1,2 (AUTHOR), Jia, Di^3,4 (AUTHOR), Zhu, Xinping¹ (AUTHOR), Yang, Jialu³ (AUTHOR), Gao, Zhipeng³ (AUTHOR), Meng, Nana⁵ (AUTHOR), Xu, Haohao³ (AUTHOR), Wang, Mengxiao¹ (AUTHOR), Chang, Shijun¹ (AUTHOR), Zhao, Mingqian³ (AUTHOR), Zhang, Shanbo³ (AUTHOR), Mu, Zichen⁴ (AUTHOR), Tang, Qiang^1,6 (AUTHOR) tangqiang1963@163.com, Zhao, Weiming¹ (AUTHOR) zhaowm1969@126.com

Fonte: PLoS ONE. 1/29/2025, Vol. 20 Issue 1, p1-17. 17p.

Termos do assunto: *CELL cycle, *ANIMAL experimentation, *ANTINEOPLASTIC agents, *INHIBITION of cellular proliferation, *HEPATOCELLULAR carcinoma

Suitability of emu (Dromaius novaehollandiae) eggs for in ovo imaging research as an alternative to conventional animal model: First experience and non‐invasive investigation of physiological embryonal development on computed tomography.

Autores: Perkas, Olga¹ (AUTHOR), Pomraenke, Marta¹ (AUTHOR), Greiser, Julia¹ (AUTHOR), Porwoll, Veronika¹ (AUTHOR), Wiegand, Steffen¹ (AUTHOR), Kuehnel, Christian¹ (AUTHOR), Winkens, Thomas¹ (AUTHOR), Freesmeyer, Martin¹ (AUTHOR) martin.freesmeyer@med.uni‐jena.de

Fonte: Acta Zoologica. Jan2025, Vol. 106 Issue 1, p55-64. 10p.

Termos do assunto: *ANIMAL experimentation, *COMPUTED tomography, *IMAGING systems, *SYSTEMS design, *OSTRICHES

Single-Cell Multi-Omics Profiling of Immune Cells Isolated from Atherosclerotic Plaques in Male ApoE Knockout Mice Exposed to Arsenic.

Autores: Makhani, Kiran^1,2, Xiuhui Yang^3,4,5,6, Dierick, France², Subramaniam, Nivetha^1,2, Gagnon, Natascha², Ebrahimian, Talin², Lehoux, Stephanie^2,4, Hao Wu⁵, Jun Ding^{1,3,4,6,7,8,9} jun.ding@mcgill.ca, Mann, Koren K.^1,2,10 koren.mann@mcgill.ca

Fonte: Environmental Health Perspectives. Jan2025, Vol. 133 Issue 1, p017007-1-017007-18. 18p.

Termos do assunto: *Environmental exposure, *Animal experimentation, *Water pollution, *Arsenic, Atherosclerosis risk factors, Biological models, T cells, Research funding, Multiomics, Epigenomics, Transcription factors, Immune system, Atherosclerosis, Dietary fats, Descriptive statistics, Mice, Messenger RNA, Pathological anatomy, Apolipoproteins, Chromosomes

Impact of Maternal BPA Exposure during Pregnancy on Obesity in Male Offspring: A Mechanistic Mouse Study of Adipose-Derived Exosomal miRNA.

Autores: Zhenyao Huang¹, Rui Niu^2,3, Qiaoqiao Xu^2,3, Rui Zhang^2,3, Weiyue Hu^2,3, Yufeng Qin^2,3, Xinru Wang^2,3, Qiujin Xu^2,4, Yankai Xia^2,3 yankaixia@njmu.edu.cn, Yun Fan^2,3 yunfan@njmu.edu.cn, Chuncheng Lu^2,3 chunchenglu@njmu.edu.cn

Fonte: Environmental Health Perspectives. Jan2025, Vol. 133 Issue 1, p017011-1-017011-19. 19p.

Termos do assunto: *Phenols, *Animal experimentation, Risk assessment, Men, Prenatal exposure delayed effects, Research funding, T-test (Statistics), MicroRNA, Cell proliferation, Pregnant women, Descriptive statistics, Mann Whitney U Test, Mice, Gene expression, Western immunoblotting, One-way analysis of variance, Childhood obesity, Data analysis software, Biological assay, Exosomes, Disease risk factors, Children, Pregnancy

Developing an Animal Model for Swenson Transanal Endorectal Pull-Through: A New Possibility for Training and Research Purposes.

Autores: Gandra de Meira, Maria Luiza¹ (AUTHOR), Buraschi Antunes, Renata¹ (AUTHOR), de Oliveira Zani, Vitoria¹ (AUTHOR), Dutra de Oliveira, Gustavo¹ (AUTHOR), Generoso, Diego² (AUTHOR), Ortolan, Erika Veruska Paiva¹ (AUTHOR), Lourenção, Pedro Luiz Toledo de Arruda¹ (AUTHOR) pedro.lourencao@unesp.br

Fonte: Journal of Investigative Surgery. Dec2024, Vol. 37 Issue 1, p1-6. 6p.

Termos do assunto: *HIRSCHSPRUNG'S disease, *ANIMAL experimentation, *POSTOPERATIVE period, *OPERATIVE surgery, *SURGICAL complications

Gastrodia elata specific miRNA attenuates neuroinflammation via modulating NF-κB signaling pathway.

Autores: Fu, Jianyuan¹ (AUTHOR), Lu, Zhong-teng¹ (AUTHOR), Wu, Guang¹ (AUTHOR), Yang, Zhe-cheng¹ (AUTHOR), Wu, Xiaoqi¹ (AUTHOR), Wang, Dan^1,2 (AUTHOR), Nie, Zuo-ming^1,2 (AUTHOR), Sheng, Qing^1,2 (AUTHOR) csheng@zstu.edu.cn

Fonte: International Journal of Neuroscience. Dec2024, Vol. 134 Issue 12, p1652-1662. 11p.

Termos do assunto: *ANIMAL experimentation, *CELLULAR signal transduction, *WESTERN immunoblotting, *NEUROINFLAMMATION, *MICRORNA

Two Hits of EDCs Three Generations Apart: Evaluating Multigenerational Anxiety-Like Behavioral Phenotypes in Female Rats Exposed to Aroclor 1221 and Vinclozolin.

Autores: Hilz, Emily N.¹, Gillette, Ross¹, Thompson, Lindsay M.¹, Ton, Lexi¹, Pham, Timothy¹, Kunkel, M. Nicole¹, Crews, David², Gore, Andrea C.¹ Andrea.gore@austin.utexas.edu

Fonte: Environmental Health Perspectives. Dec2024, Vol. 132 Issue 12, p127005-1-127005-14. 14p.

Termos do assunto: *Environmental health, *Pesticides, *Pollutants, *Environmental exposure, *Animal behavior, *Animal experimentation, *Endocrine disruptors, Biological models, Adrenocortical hormones, Hormones, Research funding, Prenatal exposure delayed effects, Anxiety, Descriptive statistics, Rats, Estradiol, One-way analysis of variance, Data analysis software, Phenotypes

Two Hits of EDCs Three Generations Apart: Evaluating Multigenerational Anxiety- Like Behavioral Phenotypes in Male Rats Exposed to Aroclor 1221 and Vinclozolin.

Autores: Hilz, Emily N.¹, Gillette, Ross¹, Thompson, Lindsay M.¹, Crews, David² andrea.gore@austin.utexas.edu, Gore, Andrea C.¹

Fonte: Environmental Health Perspectives. Dec2024, Vol. 132 Issue 12, p127006-1-127006-13. 13p.

Termos do assunto: *Environmental health, *Polychlorinated biphenyls, *Pesticides, *Pollutants, *Environmental exposure, *Animal behavior, *Animal experimentation, *Endocrine disruptors, Adrenocortical hormones, Biological models, Research funding, Data analysis, Multiple regression analysis, Anxiety, Estradiol, Rats, Analysis of variance, Statistics, Data analysis software, Phenotypes

Public controversy and citizens' attitude formation about animal research: A case for scholarship and recommendations on conflicts at the science-society interface.

Autores: Link E; Department of Communication, Johannes Gutenberg University, Mainz, Mainz, Germany., Emde-Lachmund K; Department of Journalism and Communication Research, Hanover University of Music, Drama, and Media, Hanover, Germany., Bruns S; Department of Journalism and Communication Research, Hanover University of Music, Drama, and Media, Hanover, Germany., Dittrich A; Department of Journalism and Communication Research, Hanover University of Music, Drama, and Media, Hanover, Germany., Stiesch M; Dept. of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Hanover, Germany., Haverich A; Dept. of Cardiothoracic Surgery, Transplantation, and Vascular Surgery, Hannover Medical School, Hanover, Germany., Treue S; German Primate Center-Leibniz Institute for Primate Research, Goettingen, Germany.; Initiative Tierversuche Verstehen, Muenster, Germany., Klimmt C; Department of Journalism and Communication Research, Hanover University of Music, Drama, and Media, Hanover, Germany.

Fonte: PloS one [PLoS One] 2024 Jan 03; Vol. 19 (1), pp. e0295503. Date of Electronic Publication: 2024 Jan 03 (Print Publication: 2024).

Tipo de Publicação: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Animal Experimentation*, Animals ; Fellowships and Scholarships ; Attitude ; Communication ; Research Design

Investigating material basis and molecular mechanism of Qing Cuo formula in the treatment of acne based on animal experiments, UPLC-LTQ-Orbitrap-MS and network pharmacology.

Autores: Cao Y; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Liang J; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Wang C; Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Bao X; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Li S; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Liu Q; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Zeng B; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China., Lopez DH; Department of Chemical and Environmental Engineering & Arizona Laboratory for Emerging Contaminants, University of Arizona, Tucson, AZ, USA., Yu R; National Institute of Traditional Chinese Medicine Constitution and Preventive Medicine, Beijing University of Chinese Medicine, Beijing, China.

Fonte: Pharmaceutical biology [Pharm Biol] 2023 Dec; Vol. 61 (1), pp. 973-985.

Tipo de Publicação: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE

MeSH Terms: Animal Experimentation*, Male ; Animals ; Cricetinae ; Androgens ; Network Pharmacology ; Copper

Exploring the mechanisms of action of Zengye decoction (ZYD) against Sjogren's syndrome (SS) using network pharmacology and animal experiment.

Autores: Yu J; Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China., Wang S; Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China., Yang J; Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China., Huang W; Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China., Tang B; Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China., Peng W; Department of Integrated Traditional Chinese and Western Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China., Tian J; Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

Fonte: Pharmaceutical biology [Pharm Biol] 2023 Dec; Vol. 61 (1), pp. 1286-1297.

Tipo de Publicação: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE

MeSH Terms: Animal Experimentation* , Sjogren's Syndrome*/drug therapy, Animals ; Mice ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Network Pharmacology